Improving Sample Recovery with Low-Adsorption Vials

May 10, 2016 · May 10 2016. Supelco’s Low Adsorption (LA) vials are manufactured using a process that decreases the number of hydroxyl groups on the vial's glass surface, significantly reducing surface activity while improving analytical quantitation and minimising pH shifts in the sample. This same process also removes unwanted surface metals such as

Oct 6, 2015 · Analytical challenges are exacerbated by low recovery of neuropeptides through microdialysis probes and losses due to adsorption. In this report we describe methods for improving the sampling recovery and detection sensitivity of neuropeptides for in vivo analysis.

consistency and over 2X of recovery of sialylated glycans were observed when the QuanRecovery Sample Vial was used (green bar) compared to the polypropylene vial (red bar). (B) Using the QuanRecovery Sample Vial, consistent MS response of low abundant M6P was obtained over 15 injections with the ACQUITY Premier System configuration. Conclusion

This work demonstrates how QuanRecovery Sample Vials with MaxPeak High Performance Surfaces (HPS) Technology can be used to increase recovery and stability of challenging analytes in the analysis of released glycans using HILIC-FLR/MS. Benefits Increased sample recovery leading to improve HILIC-FLR/MS assay accuracy for released glycans

Mar 15, 2022 · Low overall analyte recovery is the net result of losses that can happen for multiple reasons at all steps of sample preparation and analysis. Therefore, identifying the source(s) of analyte loss during sample preparation can help guide the optimization the bioanalysis conditions to minimize these losses.

Reduce failed assays with Waters glass and plastic autosampler vials and high sample recovery vials - certified/tested by HPLC, GC, and MS. Certified Containers Get reliable results with Waters Certified Containers, these solvent and mobile-phase bottles are ultra-clean and can be used on any LC system, including UPLC, LC/UV, and LC-MS, among

Insert vials (small capacity) may produce concentration gradients at the top and bottom due to sample adsorption, causing variation over time. Small-volume vials have a large contact area; therefore, the rate of loss due to adsorption is greater than with a standard vial. TORAST-H Glass Vials shows dramatically less adsorption

Sep 5, 2014 · In addition, alternative approaches are described to improve analyte recovery from the sample vial. The second part focuses on strategies to efficiently reduce adsorption at components of the autosampler, column and mass spectrometer.

I have focused on the development of versatile low-adsorption vials suitable for use in HPLC auto samplers, where the surface finish of the container is optimized to reduce ionic and hydrophobic sample adsorption.

Incorporation of QuanRecovery vials in sample preparation procedures can improve recovery of target analytes at trace levels in solution. pre-conditioning of glass surfaces in contact with the sample to “passivate” active adsorption sites as well as using material that exhibits low adsorption characteristics.

Improve detection limits and analysis reproducibility for peptide and protein quantification with these low adsorption plates and vials. Designed for LC-MS analysis in autosampler ready formats with low residual volumes in 700 µL 96-well plate and 300 µL sample vial formats.

Waters provides high-quality sample vials to optimize success and prevent assay failures. Glass and plastic autosampler vials undergo rigorous testing for HPLC, GC, and MS compatibility. Certified for dimensional accuracy and inertness, they enhance data quality and reproducibility. High sample recovery vials minimize loss, maximizing resources.

Assuming a constant quantity of target component is adsorbed to the vial (vials are manufactured homogeneously with no variation in vials), the issue of adsorption becomes more noticeable at lower concentrations, which then reduces calibration curve linearity.

Improve detection limits and analysis reproducibility for peptide and protein quantification with these low adsorption plates and vials. Designed for LC-MS analysis in autosampler ready formats with low residual volumes in 700 µL 96-well plate and 300 µL sample vial formats.

Reduce failed assays with Waters glass and plastic autosampler vials and high sample recovery vials - certified/tested by HPLC, GC, and MS. Certified Containers Get reliable results with Waters Certified Containers, these solvent and mobile-phase bottles are ultra-clean and can be used on any LC system, including UPLC, LC/UV, and LC-MS, among